논문 - Laboratory of Molecular Immunology

논문

Featured publications

30. Nam, G., Yeon, H. R., Park, H. B., Chang, H., Kim, J. H., Cho, B. K., Jung, H., Yi, E. C., Kim, S., An, J. Y., Lee, J. E., Lee, Y., Lee, S., Lim, H., Shon, W. J., Hwang, E. M., Ryu, H., Chang, J., Choi, K. H.*, & Choi, E. Y. CD99-mediated immunological synapse formation potentiates CAR-T cell function. Nature Communications 16(1), 7987. (2025)

29. Park, H. B., Kim, K. H., Kim, J. H., Kim, S. I., Oh, Y. M., Kang, M., Lee, S., Hwang, S., Lee, H., Lee, T. J., Park, S., Lee, J. E., Jeong, G. R., Lee, D. H., Youn, H., Choi, E. Y., Son, W. C., Chung, S. J., Chung, J., & Choi, K. H.* Improved safety of chimeric antigen receptor T cells indirectly targeting antigens via switchable adapters. Nature Communications 15(1), 9917. (2024)

28. Kim, J. H., Kim, H., Lee, A. N., Park, H. B., & Choi, K. H.* Monovalent Anti-CD3 Antibodies Effectively Eliminate the TCR-Positive fraction of TCR-Deleted Allogeneic CAR-T Cells to Prevent GVHD. Immune Network 24(6), e43. (2024)

18. Ju, J. M., Jung, M. H., Nam, G., Kim, W., Oh, S., Kim, H. D., Kim, J. Y., Chang, J., Lee, S. H., Park, G. S., Min, C. K., Lee, D. S., Kim, M. G., Choi, K. H.* & Choi, E. Y. Escape from thymic deletion and anti-leukemic effects of T cells specific for hematopoietic cell-restricted antigen. Nature Communications 9(1), 225. (2018)

17. Park, H. B., Lee, J. E., Oh, Y., Lee, S. J., Eom, H. S. & Choi, K. H.* CTLA4-CD28 chimera gene modification of t cells enhances the therapeutic efficacy of donor lymphocyte infusion for hematological malignancy. Experimental and Molecular Medicine 49(7), e360. (2017)

14. Kim, J., Ryu, S. J., Oh, K., Ju, J. M., Jeon, J. Y., Nam, G., Lee, D. S., Kim, H. R., Kim, J. Y., Chang, J., Sproule, T., Choi, K. H.*, Roopenian, D. & Choi, E. Y. Memory programming in CD8+ T-cell differentiation is intrinsic. Nature Communications 6, 7994. (2015)

13. Oh, Y. M., Park, H. B., Shin, J. H., Lee, J. E., Park, H. Y., Kho, D. H., Lee, J. S., Choi, H., Okuda, T., Kokame, K., Miyata, T., Kim, I. H., Lee, S. H., Schwartz, R. H. & Choi, K. H.* Ndrg1 is a T-cell clonal anergy factor. Nature Communications 6, 8698. (2015)

9. Shin, J. H., Park, H. B., Oh, Y. M., Lim, D. P., Lee, J. E., Seo, H. H., Lee, S. J., Eom, H. S., Kim, I. H., Lee, S. H. & Choi, K. H.* Positive conversion of negative signaling of CTLA4. Blood 119(24), 5678-5687. (2012)

All publications

27. Lee, S., Lee, H. T., Kim, Y. A., Lee, I. H., Kang, S. J., Sim, K., Park, C. G., Choi, K. H., & Youn, H. D. The optimized core peptide derived from CABIN1 efficiently inhibits calcineurin-mediated T-cell activation. Experimental and Molecular Medicine 54(5), 613-625. (2022)

26. Shin, S. P., Goh, A. R., Ju, J. M., Kang, H. G., Kim, S. J., Kim, J. K., Park, E. J., Bae, Y. S., Choi, K. H., Jung, Y. S. & Lee, S. J. Local adenoviral delivery of soluble CD200R-Ig enhances antitumor immunity by inhibiting CD200-β-catenin-driven M2 macrophage. Molecular Therapy – Oncolytics 23, 138-150. (2021)

25. Ju, J. M., Nam, G., Lee, Y. K., Jung, M., Chang, H., Kim, W., Shon, W. J., Lim, J. Y., Kim, J. Y., Chang, J., Min, C. K., Lee, D. S., Choi, K. H., Shin, D. M. & Choi, E. Y. IDO1 scavenges reactive oxygen species in myeloid-derived suppressor cells to prevent graft-versus-host disease. PNAS 118(10), e2011170118. (2021)

24. Kim, D. H., Kim, H. Y., Cho, S., Yoo, S. J., Kim, W. J., Yeon, H. R., Choi, K. H., Choi, J. M., Kang, S. W. & Lee, W. W. Induction of the IL-1RII decoy receptor by NFAT/FoxP3 blocks IL-1β-dependent response of TH17 cells. eLife 10, e61841. (2021)

23. Sim, J. H., Kim, J. H., Park, A. K., Lee, J., Kim, K. M., Shin, H. M., Kim, M., Choi, K.H., Choi, E. Y., Kang, I., Lee, D. S. & Kim, H. R. IL-7Rα low CD8+ t cells from healthy individuals are anergic with defective glycolysis. Journal of Immunology 205(11), 2968-2978. (2020)

22. Choi, E. Y., Choi, K. H., Nam, G., Kim, W. & Chung, M. H60: A Unique Murine Hematopoietic Cell-Restricted Minor Histocompatibility Antigen for Graft-versus-Leukemia Effect. Frontiers in Immunology 11, 1163. (2020)

21. Yoo, I. H., Kim, W., Choi, S. A., Kim, S. Y., Kim, H., Lim, B. C., Hwang, H., Choi, J., Kim, K. J., Kim, Y., Hyun, J. W., Kim, S. H., Choi, K. H., Kim, H. J. & Chae, J. H. Clinical spectrum of myelin oligodendrocyte glycoprotein-immunoglobulin g-associated disease in Korean children. Journal of Clinical Neurology 16(3), 461-469. (2020)

20. Kim, Y., Hyun, J. W., Woodhall, M. R., Oh, Y. M., Lee, J. E., Jung, J. Y., Kim, S. Y., Lee, M. Y., Kim, S. H., Kim, W., Irani, S. R., Waters, P., Choi, K.H.* & Kim, H. J. Refining cell-based assay to detect MOG-IgG in patients with central nervous system inflammatory diseases. Multiple Sclerosis and Related Disorders 40, 101939. (2020)

19. Lee, S. H., Soh, H., Chung, J. H., Cho, E. H., Lee, S. J., Ju, J. M., Sheen, J. H., Kim, H., Oh, S. J., Lee, S. J., Chung, J., Choi, K. H., Kim, S. Y. & Ryu, J. S. Feasibility of real-time in vivo 89Zr-DFO-labeled CAR T-cell trafficking using PET imaging. PLoS ONE 15(1), e0223814. (2020)

16. Kim, Y., Kim, G., Kong, B. S., Lee, J. E., Oh, Y. M., Hyun, J. W., Kim, S. H., Joung, A. R., Kim, B. J., Choi, K. H.* & Kim, H. J. Large-scale in-house cell-based assay for evaluating the serostatus in patients with neuromyelitis optica spectrum disorder. Journal of Clinical Neurology 13(2), 175-180. (2017)

15. Shin, J. H., Park, H. B. & Choi, K. H.* Enhanced anti-tumor reactivity of cytotoxic T lymphocytes expressing PD-1 decoy. Immune Network 16(2), 134-139. (2016)

12. Goh, A. R., Shin, S. P., Jung, N. R., Ryu, C. H., Eom, H. S., Lee, J. H., Choi, K. H.*, Lee, S. J. & Jung, Y. S. Low-dose cisplatin converts the tumor microenvironment. Cancer Letters 356(2), 743-750. (2015)

11. Kim, J. H., Yoon, E. K., Chung, H. J., Park, S. Y., Hong, K. M., Lee, C. H., Lee, Y. S., Choi, K. H.*, Yang, Y., Kim, K. & Kim, I. H. P53 acetylation enhances Taxol-induced apoptosis. Apoptosis 18(1), 110-120. (2013)

10. Shin, S. P., Seo, H. H., Shin, J. H., Park, H. B., Lim, D. P., Eom, H. S., Bae, Y. S., Kim, I. H., Choi, K. H.* & Lee, S. J. Adenovirus expressing both thymidine kinase and soluble PD1. Molecular Therapy 21(3), 688-695. (2013)

8. Kim, W., Lee, J. E., Li, X. F., Kim, S. H., Han, B. G., Lee, B. I., Kim, J. K., Choi, K. H.* & Kim, H. J. Quantitative measurement of anti-aquaporin-4 antibodies by ELISA. Multiple Sclerosis Journal 18(5), 578-586. (2012)

7. Cho, S. Y., Jeong, E. M., Lee, J. H., Kim, H. J., Lim, J., Kim, C. W., Shin, D. M., Jeon, J. H., Choi, K. H.* & Kim, I. G. Doxorubicin induces the persistent activation of intracellular transglutaminase 2. Molecules and Cells 33(3), 235-241. (2012)

6. Kwak, H. J., Kim, Y. J., Chun, K. R., Woo, Y. M., Park, S. J., Jeong, J. A., Jo, S. H., Kim, T. H., Min, H. S., Chae, J. S., Choi, E. J., Kim, G., Shin, S. H., Gwak, H. S., Kim, S. K., Hong, E. K., Lee, G. K., Choi, K. H., Kim, J. H. & Yoo, H., Park, J. B. & Lee, S. H. Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas. Oncogene 30(21), 2433-2442. (2011)

5. Kim, Y. H., Sung, H. J., Kim, S., Kim, E. O., Lee, J. W., Moon, J. Y., Choi, K. H., Jung, J. E., Lee, Y., Koh, S. S., Rhee, S. G., Heo, K. & Kim, I. H. An RNA aptamer that specifically binds PAUF. Cancer Letters 313(1), 76-83. (2011)

4. Hong, D. M., Kim, C. S., Eom, W., Choi, K. H., Oh, Y. J., Jung, S. J. & Kim, H. S. Interactions of midazolam and propofol on GABAA receptors. Anesthesia and Analgesia 112(5), 1096-1102. (2011)

3. Eom, W., Lee, J. M., Park, J., Choi, K. H., Jung, S. J. & Kim, H. S. The effects of midazolam and sevoflurane on the GABAA receptors. Korean journal of anesthesiology 60(2), 109-118. (2011)

2. Cho, S. Y., Choi, K. H., Jeon, J. H., Kim, C. W., Shin, D. M., Lee, J. B., Lee, S. E., Kim, C. S., Park, J. S., Jeong, E. M., Jang, G. Y., Song, K. Y. & Kim, I. G. Differential alternative splicing of human transglutaminase 4. Experimental and Molecular Medicine 42(4), 310-318. (2010)

1. Lee, J. S., Lee, J. E., Oh, Y. M., Park, J. B., Choi, H., Choi, C. Y., Kim, I. H., Lee, S. H. & Choi, K. H.* Recruitment of sprouty1 to immune synapse regulates T cell receptor signaling. Journal of Immunology 183(11), 7178-7186. (2009)